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Total saponin from Korean Red Ginseng inhibits binding of adhesive proteins to glycoprotein IIb/IIIa via phosphorylation of VASP (Ser(157)) and dephosphorylation of PI3K and Akt

BACKGROUND: Binding of adhesive proteins (i.e., fibrinogen, fibronectin, vitronectin) to platelet integrin glycoprotein IIb/IIIa (αIIb/β(3)) by various agonists (thrombin, collagen, adenosine diphosphate) involve in strength of thrombus. This study was carried out to evaluate the antiplatelet effect...

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Detalles Bibliográficos
Autores principales:	Kwon, Hyuk-Woo, Shin, Jung-Hae, Cho, Hyun-Jeong, Rhee, Man Hee, Park, Hwa-Jin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703804/ https://www.ncbi.nlm.nih.gov/pubmed/26843825 http://dx.doi.org/10.1016/j.jgr.2015.05.004

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