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The Rho Termination Factor of Clostridium botulinum Contains a Prion-Like Domain with a Highly Amyloidogenic Core

Prion-like proteins can switch between a soluble intrinsically disordered conformation and a highly ordered amyloid assembly. This conformational promiscuity is encoded in specific sequence regions, known as prion domains (PrDs). Prions are best known as the causative factors of neurological disease...

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Detalles Bibliográficos
Autores principales: Pallarès, Irantzu, Iglesias, Valentin, Ventura, Salvador
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703818/
https://www.ncbi.nlm.nih.gov/pubmed/26779170
http://dx.doi.org/10.3389/fmicb.2015.01516

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