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The Rho Termination Factor of Clostridium botulinum Contains a Prion-Like Domain with a Highly Amyloidogenic Core
Prion-like proteins can switch between a soluble intrinsically disordered conformation and a highly ordered amyloid assembly. This conformational promiscuity is encoded in specific sequence regions, known as prion domains (PrDs). Prions are best known as the causative factors of neurological disease...
Autores principales: | Pallarès, Irantzu, Iglesias, Valentin, Ventura, Salvador |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703818/ https://www.ncbi.nlm.nih.gov/pubmed/26779170 http://dx.doi.org/10.3389/fmicb.2015.01516 |
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