Exome-wide association analysis reveals novel coding sequence variants associated with lipid traits in Chinese

Blood lipids are important risk factors for coronary artery disease (CAD). Here we perform an exome-wide association study by genotyping 12,685 Chinese, using a custom Illumina HumanExome BeadChip, to identify additional loci influencing lipid levels. Single-variant association analysis on 65,671 si...

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Detalles Bibliográficos
Autores principales: Tang, Clara S., Zhang, He, Cheung, Chloe Y. Y., Xu, Ming, Ho, Jenny C. Y., Zhou, Wei, Cherny, Stacey S., Zhang, Yan, Holmen, Oddgeir, Au, Ka-Wing, Yu, Haiyi, Xu, Lin, Jia, Jia, Porsch, Robert M., Sun, Lijie, Xu, Weixian, Zheng, Huiping, Wong, Lai-Yung, Mu, Yiming, Dou, Jingtao, Fong, Carol H. Y., Wang, Shuyu, Hong, Xueyu, Dong, Liguang, Liao, Yanhua, Wang, Jiansong, Lam, Levina S. M., Su, Xi, Yan, Hua, Yang, Min-Lee, Chen, Jin, Siu, Chung-Wah, Xie, Gaoqiang, Woo, Yu-Cho, Wu, Yangfeng, Tan, Kathryn C. B., Hveem, Kristian, Cheung, Bernard M. Y., Zöllner, Sebastian, Xu, Aimin, Eugene Chen, Y, Jiang, Chao Qiang, Zhang, Youyi, Lam, Tai-Hing, Ganesh, Santhi K., Huo, Yong, Sham, Pak C., Lam, Karen S. L., Willer, Cristen J., Tse, Hung-Fat, Gao, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703860/
https://www.ncbi.nlm.nih.gov/pubmed/26690388
http://dx.doi.org/10.1038/ncomms10206

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