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T7 replisome directly overcomes DNA damage
Cells and viruses possess several known ‘restart' pathways to overcome lesions during DNA replication. However, these ‘bypass' pathways leave a gap in replicated DNA or require recruitment of accessory proteins, resulting in significant delays to fork movement or even cell division arrest....
Autores principales: | Sun, Bo, Pandey, Manjula, Inman, James T., Yang, Yi, Kashlev, Mikhail, Patel, Smita S., Wang, Michelle D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703881/ https://www.ncbi.nlm.nih.gov/pubmed/26675048 http://dx.doi.org/10.1038/ncomms10260 |
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