RSV-specific airway resident memory CD8+ T cells and differential disease severity after experimental human infection

In animal models, resident memory CD8+ T (Trm) cells assist in respiratory virus elimination but their importance in man has not been determined. Here, using experimental human respiratory syncytial virus (RSV) infection, we investigate systemic and local virus-specific CD8+ T-cell responses in adul...

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Detalles Bibliográficos
Autores principales: Jozwik, Agnieszka, Habibi, Maximillian S., Paras, Allan, Zhu, Jie, Guvenel, Aleks, Dhariwal, Jaideep, Almond, Mark, Wong, Ernie H. C., Sykes, Annemarie, Maybeno, Matthew, Del Rosario, Jerico, Trujillo-Torralbo, Maria-Belen, Mallia, Patrick, Sidney, John, Peters, Bjoern, Kon, Onn Min, Sette, Alessandro, Johnston, Sebastian L., Openshaw, Peter J., Chiu, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703893/
https://www.ncbi.nlm.nih.gov/pubmed/26687547
http://dx.doi.org/10.1038/ncomms10224

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