Accumulation of differentiating intestinal stem cell progenies drives tumorigenesis

Stem cell self-renewal and differentiation are coordinated to maintain tissue homeostasis and prevent cancer. Mutations causing stem cell proliferation are traditionally the focus of cancer studies. However, the contribution of the differentiating stem cell progenies in tumorigenesis is poorly chara...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhai, Zongzhao, Kondo, Shu, Ha, Nati, Boquete, Jean-Philippe, Brunner, Michael, Ueda, Ryu, Lemaitre, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703904/
https://www.ncbi.nlm.nih.gov/pubmed/26690827
http://dx.doi.org/10.1038/ncomms10219

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703904/
https://www.ncbi.nlm.nih.gov/pubmed/26690827
http://dx.doi.org/10.1038/ncomms10219

Ejemplares similares