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Drug response in organoids generated from frozen primary tumor tissues
Primary tumor organoids grown in three-dimensional culture provide an excellent platform for studying tumor progression, invasion, and drug response. However, organoid generation protocols require fresh tumor tissue, which limits organoid research and clinical use. This study investigates cellular m...
Autores principales: | Walsh, Alex J., Cook, Rebecca S., Sanders, Melinda E., Arteaga, Carlos L., Skala, Melissa C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703961/ https://www.ncbi.nlm.nih.gov/pubmed/26738962 http://dx.doi.org/10.1038/srep18889 |
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