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Drug response in organoids generated from frozen primary tumor tissues

Primary tumor organoids grown in three-dimensional culture provide an excellent platform for studying tumor progression, invasion, and drug response. However, organoid generation protocols require fresh tumor tissue, which limits organoid research and clinical use. This study investigates cellular m...

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Detalles Bibliográficos
Autores principales: Walsh, Alex J., Cook, Rebecca S., Sanders, Melinda E., Arteaga, Carlos L., Skala, Melissa C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703961/
https://www.ncbi.nlm.nih.gov/pubmed/26738962
http://dx.doi.org/10.1038/srep18889

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