Cargando…

Elderly male smokers with right lung tumors are viable candidates for KRAS mutation screening

Genetic aberrations in tumor driver genes provide specific molecular targets for therapeutic intervention, which can greatly improve therapeutic outcomes. Here, we analyzed the mutational frequency of EGFR and KRAS gene, as well as EML4-ALK rearrangement, and summarized the clinicopathological chara...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Yang, Shi, Chun, Sun, Hui, Yin, Wei, Zhou, Xiao, Zhang, Lei, Jiang, Gening
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703983/ https://www.ncbi.nlm.nih.gov/pubmed/26739511 http://dx.doi.org/10.1038/srep18566

Ejemplares similares

Differences in EGFR and KRAS mutation spectra in lung adenocarcinoma of never and heavy smokers
por: TAKAMOCHI, KAZUYA, et al.
Publicado: (2013)

Identification of somatic mutations in EGFR/KRAS/ALK-negative lung adenocarcinoma in never-smokers
por: Ahn, Jin Woo, et al.
Publicado: (2014)

Snapback Primer Mediated Clamping PCR for Detection of EGFR and KRAS Mutations in NSCLC Patients by High Resolution Melting Analysis
por: Sun, Haiyan, et al.
Publicado: (2014)

Gross Hematuria in an Elderly Smoker Male Due to Eosinophilic Cystitis
por: Al Sbihi, Ali F, et al.
Publicado: (2020)

EGFR and KRAS Mutations in Lung Parenchyma of Subjects With EGFR/KRAS Wild-Type Lung Adenocarcinoma
por: Chalela, Roberto, et al.
Publicado: (2021)

Burden of male hardcore smokers and its characteristics among those eligible for lung cancer screening
por: Park, Dong Won, et al.
Publicado: (2020)

KRAS and EGFR mutations coexisting in lung adenocarcinoma
por: Sousa, Vitor, et al.
Publicado: (2010)

EGFR and KRAS Mutations in Patients With Adenocarcinoma of the Lung
por: Jang, Tae Won, et al.
Publicado: (2009)

KRAS Mutations in Squamous Cell Carcinomas of the Lung
por: Acker, Fabian, et al.
Publicado: (2021)

EGFR, ALK, RET, KRAS and BRAF alterations in never-smokers with non-small cell lung cancer
por: DONG, YU, et al.
Publicado: (2016)

A Real-World Study in Advanced Non–Small Cell Lung Cancer with KRAS Mutations
por: Lei, Lei, et al.
Publicado: (2019)

Realgar-induced KRAS mutation lung cancer cell death via KRAS/Raf/MAPK mediates ferroptosis
por: Liu, Xiaofeng, et al.
Publicado: (2022)

Case Report: Chemotherapy-free treatment with camrelizumab and anlotinib for elderly patients with KRAS and TP53 mutated advanced lung cancer
por: Qi, Wenbo, et al.
Publicado: (2023)

Epidermal Growth Factor Receptor Mutations and the Clinical Outcome in Male Smokers with Squamous Cell Carcinoma of Lung
por: Park, Se Hoon, et al.
Publicado: (2009)

Unique circulating microRNAs in relation to EGFR mutation status in Japanese smoker male with lung adenocarcinoma
por: Ito, Sachio, et al.
Publicado: (2017)

Discovery of decreased ferroptosis in male colorectal cancer patients with KRAS mutations
por: Yan, Hong, et al.
Publicado: (2023)

Discovery of decreased ferroptosis in male colorectal cancer patients with KRAS mutations
por: Yan, Hong, et al.
Publicado: (2023)

Eprobe-mediated screening system for somatic mutations in the KRAS locus
por: ATSUMI, JUN, et al.
Publicado: (2015)

Apatinib in the treatment of advanced lung adenocarcinoma with KRAS mutation
por: Zeng, Da-xiong, et al.
Publicado: (2017)

Cost-effectiveness of screening smokers and ex-smokers for lung cancer in the Netherlands in different age groups
por: Al Khayat, Mohamed N. M. T., et al.
Publicado: (2022)

Clinicopathologic characteristics and survival outcome in patients with advanced lung adenocarcinoma and KRAS mutation
por: Yang, Shifeng, et al.
Publicado: (2018)

KRAS mutation analysis in ductal carcinoma of the pancreas; prognostic implications in elderly patients
por: Oldani, Alberto, et al.
Publicado: (2013)

Biomarkers of lung cancer for screening and in never-smokers—a narrative review
por: Stephens, Edward K. H., et al.
Publicado: (2023)

Diffuse Idiopathic Skeletal Hyperostosis: Persistent Sore Throat and Dysphagia in an Elderly Smoker Male
por: Goico-Alburquerque, Ana, et al.
Publicado: (2017)

Endobronchial mass in an elderly smoker
por: Dutta, Roman, et al.
Publicado: (2010)

PIK3CA Mutations Frequently Coexist with EGFR/KRAS Mutations in Non-Small Cell Lung Cancer and Suggest Poor Prognosis in EGFR/KRAS Wildtype Subgroup
por: Wang, Lei, et al.
Publicado: (2014)

EGFR, KRAS, BRAF, PTEN, and PIK3CA mutation in plasma of small cell lung cancer patients
por: Lu, Hong-Yang, et al.
Publicado: (2018)

KRAS Mutations and Primary Resistance of Lung Adenocarcinomas to Gefitinib or Erlotinib
por: Pao, William, et al.
Publicado: (2005)

Frequency and Spectrum of KRAS Mutations in Moroccan Patients with Lung Adenocarcinoma
por: Elghissassi, Ibrahim, et al.
Publicado: (2014)

Realities of KRAS-mutated non-small cell lung cancer
por: Min, Young Joo
Publicado: (2017)

Metachronous primary lung adenocarcinomas harboring distinct KRAS mutations
por: Hu, Yan, et al.
Publicado: (2020)

Evaluation of KRAS Concomitant Mutations in Advanced Lung Adenocarcinoma Patients
por: Aran, Veronica, et al.
Publicado: (2021)

Effects of breathing exercises on lung capacity and muscle activities of elderly smokers
por: Jun, Hyun-Ju, et al.
Publicado: (2016)

The implicit beliefs and implicit behavioral tendencies towards smoking-related cues among Chinese male smokers and non-smokers
por: Ren, Lei, et al.
Publicado: (2019)

Comparison of Periodontal Status Between Male Exclusive Narghile Smokers and Male Exclusive Cigarette Smokers
por: Khemiss, Mehdi, et al.
Publicado: (2019)

KRAS-mutation incidence and prognostic value are metastatic site-specific in lung adenocarcinoma: poor prognosis in patients with KRAS mutation and bone metastasis
por: Lohinai, Zoltan, et al.
Publicado: (2017)

Case Report: Outcome of Osimertinib Treatment in Lung Adenocarcinoma Patients With Acquired KRAS Mutations
por: Xiu, Weigang, et al.
Publicado: (2021)

KRAS/LKB1 and KRAS/TP53 co-mutations create divergent immune signatures in lung adenocarcinomas
por: Gu, Meichen, et al.
Publicado: (2021)

Distinct immune microenvironment of lung adenocarcinoma in never-smokers from smokers
por: Luo, Wenxin, et al.
Publicado: (2023)

An Elderly Male with a Chronic Rash on the Right Foot
por: Fatima, Sakeena, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_2d5ol0eldq74dhfjmvp1oi4ntc