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Regulation of the Target of Rapamycin and Other Phosphatidylinositol 3-Kinase-Related Kinases by Membrane Targeting

Phosphatidylinositol 3-kinase-related kinases (PIKKs) play vital roles in the regulation of cell growth, proliferation, survival, and consequently metabolism, as well as in the cellular response to stresses such as ionizing radiation or redox changes. In humans six family members are known to date,...

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Detalles Bibliográficos
Autores principales: De Cicco, Maristella, Abd Rahim, Munirah S., Dames, Sonja A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703999/
https://www.ncbi.nlm.nih.gov/pubmed/26426064
http://dx.doi.org/10.3390/membranes5040553