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A common TLR1 polymorphism is associated with higher parasitaemia in a Southeast Asian population with Plasmodium falciparum malaria

BACKGROUND: The factors leading to poor outcomes in malaria infection are incompletely understood. Common genetic variation exists in the human genes for Toll like receptors (TLRs) that alter host responses to pathogen-associated molecular patterns. Genetic variation in TLR1 and TLR6 could alter the...

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Detalles Bibliográficos
Autores principales:	Hahn, William O., Harju-Baker, Susanna, Erdman, Laura K., Krudsood, Srivicha, Kain, Kevin C., Wurfel, Mark M., Liles, Wayne C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4704253/ https://www.ncbi.nlm.nih.gov/pubmed/26738805 http://dx.doi.org/10.1186/s12936-015-1071-y

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