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Molecular pathogenesis of sporadic colorectal cancers

Colorectal cancer (CRC) results from the progressive accumulation of genetic and epigenetic alterations that lead to the transformation of normal colonic mucosa to adenocarcinoma. Approximately 75% of CRCs are sporadic and occur in people without genetic predisposition or family history of CRC. Duri...

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Detalles Bibliográficos
Autores principales:	Yamagishi, Hidetsugu, Kuroda, Hajime, Imai, Yasuo, Hiraishi, Hideyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4704376/ https://www.ncbi.nlm.nih.gov/pubmed/26738600 http://dx.doi.org/10.1186/s40880-015-0066-y

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