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CXCL5 signaling is a shared pathway of neuroinflammation and blood–brain barrier injury contributing to white matter injury in the immature brain

BACKGROUND: In very preterm infants, white matter injury is a prominent brain injury, and hypoxic ischemia (HI) and infection are the two primary pathogenic factors of this injury. Microglia and microvascular endothelial cells closely interact; therefore, a common signaling pathway may cause neuroin...

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Detalles Bibliográficos
Autores principales: Wang, Lin-Yu, Tu, Yi-Fang, Lin, Yung-Chieh, Huang, Chao-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4704424/
https://www.ncbi.nlm.nih.gov/pubmed/26738635
http://dx.doi.org/10.1186/s12974-015-0474-6