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Activation of Ca(2+)‐activated Cl(−) channel ANO1 by localized Ca(2+) signals

Ca(2+)‐activated chloride channels (CaCCs) regulate numerous physiological processes including epithelial transport, smooth muscle contraction and sensory processing. Anoctamin‐1 (ANO1, TMEM16A) is a principal CaCC subunit in many cell types, yet our understanding of the mechanisms of ANO1 activatio...

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Detalles Bibliográficos
Autores principales: Jin, Xin, Shah, Sihab, Du, Xiaona, Zhang, Hailin, Gamper, Nikita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4704509/
https://www.ncbi.nlm.nih.gov/pubmed/25398532
http://dx.doi.org/10.1113/jphysiol.2014.275107