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Cytokine preconditioning of engineered cartilage provides protection against interleukin-1 insult
BACKGROUND: During osteoarthritis and following surgical procedures, the environment of the knee is rich in proinflammatory cytokines such as IL-1. Introduction of tissue-engineered cartilage constructs to a chemically harsh milieu may limit the functionality of the implanted tissue over long period...
Autores principales: | Tan, Andrea R., VandenBerg, Curtis D., Attur, Mukundan, Abramson, Steven B., Knight, Martin M, Bulinski, J. Chloe, Ateshian, Gerard A., Cook, James L, Hung, Clark T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4704536/ https://www.ncbi.nlm.nih.gov/pubmed/26667364 http://dx.doi.org/10.1186/s13075-015-0876-y |
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