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Inflammatory but not apoptotic death of granulocytes citrullinates fibrinogen

BACKGROUND: Neutrophil activation induces citrullination of intracellular targets of anticitrullinated peptide antibodies (ACPA), which are specific for rheumatoid arthritis (RA). Citrullinated fibrinogen is bound by ACPA but it is less well understood how extracellular proteins are citrullinated. T...

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Detalles Bibliográficos
Autores principales: Blachère, Nathalie E., Parveen, Salina, Fak, John, Frank, Mayu O., Orange, Dana E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4704541/
https://www.ncbi.nlm.nih.gov/pubmed/26684871
http://dx.doi.org/10.1186/s13075-015-0890-0