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Inflammatory but not apoptotic death of granulocytes citrullinates fibrinogen
BACKGROUND: Neutrophil activation induces citrullination of intracellular targets of anticitrullinated peptide antibodies (ACPA), which are specific for rheumatoid arthritis (RA). Citrullinated fibrinogen is bound by ACPA but it is less well understood how extracellular proteins are citrullinated. T...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4704541/ https://www.ncbi.nlm.nih.gov/pubmed/26684871 http://dx.doi.org/10.1186/s13075-015-0890-0 |