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IgG4-related sialadenitis: IgG4 is helpful, but biopsies are still crucial

IgG4-related disease is rare, but a frequent differential diagnosis for malignant and for autoimmune diseases. Li and colleagues report the largest cohort of patients with IgG4-related sialadenitis. The observations reveal that the most important diagnostic step is obtaining biopsies. In addition, t...

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Detalles Bibliográficos
Autores principales: Witte, Torsten, Schulze-Koops, Hendrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4704542/
https://www.ncbi.nlm.nih.gov/pubmed/26684829
http://dx.doi.org/10.1186/s13075-015-0888-7
Descripción
Sumario:IgG4-related disease is rare, but a frequent differential diagnosis for malignant and for autoimmune diseases. Li and colleagues report the largest cohort of patients with IgG4-related sialadenitis. The observations reveal that the most important diagnostic step is obtaining biopsies. In addition, the IgG4 serum concentration may be a biomarker for the disease progression.