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Automated Learning of Subcellular Variation among Punctate Protein Patterns and a Generative Model of Their Relation to Microtubules
Characterizing the spatial distribution of proteins directly from microscopy images is a difficult problem with numerous applications in cell biology (e.g. identifying motor-related proteins) and clinical research (e.g. identification of cancer biomarkers). Here we describe the design of a system th...
Autores principales: | Johnson, Gregory R., Li, Jieyue, Shariff, Aabid, Rohde, Gustavo K., Murphy, Robert F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4704559/ https://www.ncbi.nlm.nih.gov/pubmed/26624011 http://dx.doi.org/10.1371/journal.pcbi.1004614 |
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