Crystal structure of (RS)-(4-chloro­phen­yl)(pyridin-2-yl)methanol

In the title racemic compound, C(12)H(10)ClNO, the dihedral angle between the benzene and pyridine rings is 74.34 (6)°. In the crystal, the mol­ecules are linked by O—H⋯N hydrogen bonds, forming zigzag C(5) [001] chains in which alternating R- and S-configuration mol­ecules are related by c-glide sy...

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Autores principales: Narayana, Badiadka, Sarojini, Balladka K., Yathirajan, Hemmige S., Rathore, Ravindranath, Glidewell, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2016
Materias:
Research Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4704747/
https://www.ncbi.nlm.nih.gov/pubmed/26870589
http://dx.doi.org/10.1107/S2056989015023154
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author Narayana, Badiadka
Sarojini, Balladka K.
Yathirajan, Hemmige S.
Rathore, Ravindranath
Glidewell, Christopher
author_facet Narayana, Badiadka
Sarojini, Balladka K.
Yathirajan, Hemmige S.
Rathore, Ravindranath
Glidewell, Christopher
author_sort Narayana, Badiadka
collection PubMed
description In the title racemic compound, C(12)H(10)ClNO, the dihedral angle between the benzene and pyridine rings is 74.34 (6)°. In the crystal, the mol­ecules are linked by O—H⋯N hydrogen bonds, forming zigzag C(5) [001] chains in which alternating R- and S-configuration mol­ecules are related by c-glide symmetry. In addition, inversion-related pairs of mol­ecules are linked into dimers by pairs of weak C—Cl⋯π(pyrid­yl) inter­actions, which link the hydrogen-bonded chains into (100) sheets. Structural comparisons are drawn with a number of related compounds.
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spelling pubmed-47047472016-02-11 Crystal structure of (RS)-(4-chloro­phen­yl)(pyridin-2-yl)methanol Narayana, Badiadka Sarojini, Balladka K. Yathirajan, Hemmige S. Rathore, Ravindranath Glidewell, Christopher Acta Crystallogr E Crystallogr Commun Research Communications In the title racemic compound, C(12)H(10)ClNO, the dihedral angle between the benzene and pyridine rings is 74.34 (6)°. In the crystal, the mol­ecules are linked by O—H⋯N hydrogen bonds, forming zigzag C(5) [001] chains in which alternating R- and S-configuration mol­ecules are related by c-glide symmetry. In addition, inversion-related pairs of mol­ecules are linked into dimers by pairs of weak C—Cl⋯π(pyrid­yl) inter­actions, which link the hydrogen-bonded chains into (100) sheets. Structural comparisons are drawn with a number of related compounds. International Union of Crystallography 2016-01-01 /pmc/articles/PMC4704747/ /pubmed/26870589 http://dx.doi.org/10.1107/S2056989015023154 Text en © Narayana et al. 2016 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Research Communications
Narayana, Badiadka
Sarojini, Balladka K.
Yathirajan, Hemmige S.
Rathore, Ravindranath
Glidewell, Christopher
Crystal structure of (RS)-(4-chloro­phen­yl)(pyridin-2-yl)methanol
title Crystal structure of (RS)-(4-chloro­phen­yl)(pyridin-2-yl)methanol
title_full Crystal structure of (RS)-(4-chloro­phen­yl)(pyridin-2-yl)methanol
title_fullStr Crystal structure of (RS)-(4-chloro­phen­yl)(pyridin-2-yl)methanol
title_full_unstemmed Crystal structure of (RS)-(4-chloro­phen­yl)(pyridin-2-yl)methanol
title_short Crystal structure of (RS)-(4-chloro­phen­yl)(pyridin-2-yl)methanol
title_sort crystal structure of (rs)-(4-chloro­phen­yl)(pyridin-2-yl)methanol
topic Research Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4704747/
https://www.ncbi.nlm.nih.gov/pubmed/26870589
http://dx.doi.org/10.1107/S2056989015023154
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