Propranolol Targets Hemangioma Stem Cells via cAMP and Mitogen-Activated Protein Kinase Regulation

Infantile hemangiomas (IHs) are the most common vascular tumor and arise from a hemangioma stem cell (HemSC). Propranolol has proved efficacious for problematic IHs. Propranolol is a nonselective β-adrenergic receptor (βAR) antagonist that can lower cAMP levels and activate the mitogen-activated pro...

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Detalles Bibliográficos
Autores principales: Munabi, Naikhoba C.O., England, Ryan W., Edwards, Andrew K., Kitajewski, Alison A., Tan, Qian Kun, Weinstein, Andrew, Kung, Justin E., Wilcox, Maya, Kitajewski, Jan K., Shawber, Carrie J., Wu, June K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AlphaMed Press 2016
Materias:
Tissue-Specific Progenitor and Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4704871/
https://www.ncbi.nlm.nih.gov/pubmed/26574555
http://dx.doi.org/10.5966/sctm.2015-0076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4704871/
https://www.ncbi.nlm.nih.gov/pubmed/26574555
http://dx.doi.org/10.5966/sctm.2015-0076

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