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Mass spectrometry imaging of amino neurotransmitters: a comparison of derivatization methods and application in mouse brain tissue

The detection of small polar compounds such as amino neurotransmitters by MALDI mass spectrometry imaging has been hindered by low-detection sensitivity and background interferences. Recently, several of on-tissue chemical derivatization strategies have been independently reported that enable their...

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Detalles Bibliográficos
Autores principales: Esteve, Clara, Tolner, Else A., Shyti, Reinald, van den Maagdenberg, Arn M. J. M., McDonnell, Liam A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705126/
https://www.ncbi.nlm.nih.gov/pubmed/26793043
http://dx.doi.org/10.1007/s11306-015-0926-0