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A Single Glycan at the 99-Loop of Human Kallikrein-related Peptidase 2 Regulates Activation and Enzymatic Activity

Human kallikrein-related peptidase 2 (KLK2) is a key serine protease in semen liquefaction and prostate cancer together with KLK3/prostate-specific antigen. In order to decipher the function of its potential N-glycosylation site, we produced pro-KLK2 in Leishmania tarentolae cells and compared it wi...

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Detalles Bibliográficos
Autores principales:	Skala, Wolfgang, Magdolen, Viktor, Briza, Peter, Biniossek, Martin L., Schilling, Oliver, Kellermann, Josef, Brandstetter, Hans, Goettig, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2016
Materias:	Enzymology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705380/ https://www.ncbi.nlm.nih.gov/pubmed/26582203 http://dx.doi.org/10.1074/jbc.M115.691097

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