A new monoclonal antibody (CAL2) detects CALRETICULIN mutations in formalin-fixed and paraffin-embedded bone marrow biopsies

Recent advances in the diagnostic of myeloproliferative neoplasms (MPNs) discovered CALRETICULIN (CALR) mutations as a major driver in these disorders. In contrast to JAK2 mutations being mainly associated with polycythaemia vera, CALR mutations are only associated with primary myelofibrosis (PMF) a...

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Detalles Bibliográficos
Autores principales: Stein, H, Bob, R, Dürkop, H, Erck, C, Kämpfe, D, Kvasnicka, H-M, Martens, H, Roth, A, Streubel, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705422/
https://www.ncbi.nlm.nih.gov/pubmed/26202929
http://dx.doi.org/10.1038/leu.2015.192

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