Cargando…
Metabolic plasticity in CLL: adaptation to the hypoxic niche
Metabolic transformation in cancer is increasingly well understood. However, little is known about the metabolic responses of cancer cells that permit their survival in different microenvironments. We have used a nuclear magnetic resonance based approach to monitor metabolism in living primary chron...
Autores principales: | Koczula, K M, Ludwig, C, Hayden, R, Cronin, L, Pratt, G, Parry, H, Tennant, D, Drayson, M, Bunce, C M, Khanim, F L, Günther, U L |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705428/ https://www.ncbi.nlm.nih.gov/pubmed/26202928 http://dx.doi.org/10.1038/leu.2015.187 |
Ejemplares similares
-
Does the pursuit of scientific excellence serve or hamper translational medical research: an historical perspective from hematological malignancies
por: Bunce, Chris M., et al.
Publicado: (2022) -
Hypoxia Triggers Major Metabolic Changes in AML Cells without Altering Indomethacin-Induced TCA Cycle Deregulation
por: Lodi, Alessia, et al.
Publicado: (2010) -
Selective AKR1C3 inhibitors do not recapitulate the anti-leukaemic activities of the pan-AKR1C inhibitor medroxyprogesterone acetate
por: Khanim, F, et al.
Publicado: (2014) -
Malonate as a ROS product is associated with pyruvate carboxylase activity in acute myeloid leukaemia cells
por: Reed, Michelle A. C., et al.
Publicado: (2016) -
Proton NMR-Based Metabolite Analyses of Archived Serial Paired Serum and Urine Samples from Myeloma Patients at Different Stages of Disease Activity Identifies Acetylcarnitine as a Novel Marker of Active Disease
por: Lodi, Alessia, et al.
Publicado: (2013)