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Measurement of lentiviral vector titre and copy number by cross-species duplex quantitative PCR

Lentiviruses are the vectors of choice for many preclinical studies and clinical applications of gene therapy. Accurate measurement of biological vector titre before treatment is a prerequisite for vector dosing, and the calculation of vector integration sites per cell after treatment is as critical...

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Detalles Bibliográficos
Autores principales:	Christodoulou, I, Patsali, P, Stephanou, C, Antoniou, M, Kleanthous, M, Lederer, C W
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Short Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705430/ https://www.ncbi.nlm.nih.gov/pubmed/26202078 http://dx.doi.org/10.1038/gt.2015.60

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