Cargando…

Cediranib combined with carboplatin and paclitaxel in patients with metastatic or recurrent cervical cancer (CIRCCa): a randomised, double-blind, placebo-controlled phase 2 trial

BACKGROUND: Patients treated with standard chemotherapy for metastatic or relapsed cervical cancer respond poorly to conventional chemotherapy (response achieved in 20–30% of patients) with an overall survival of less than 1 year. High tumour angiogenesis and high concentrations of intratumoural VEG...

Descripción completa

Detalles Bibliográficos
Autores principales:	Symonds, R Paul, Gourley, Charlie, Davidson, Susan, Carty, Karen, McCartney, Elaine, Rai, Debbie, Banerjee, Susana, Jackson, David, Lord, Rosemary, McCormack, Mary, Hudson, Emma, Reed, Nicholas, Flubacher, Maxine, Jankowska, Petra, Powell, Melanie, Dive, Caroline, West, Catharine M L, Paul, James
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lancet Pub. Group 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705431/ https://www.ncbi.nlm.nih.gov/pubmed/26474517 http://dx.doi.org/10.1016/S1470-2045(15)00220-X

Ejemplares similares

Multi-Center Randomized Phase II Study Comparing Cediranib plus Gefitinib with Cediranib plus Placebo in Subjects with Recurrent/Progressive Glioblastoma
por: Brown, Nicholas, et al.
Publicado: (2016)

CircCA12 Promotes Malignant Process via Sponging miR-1184 and Upregulating RAS Family in Bladder Cancer
por: Jiang, Lijuan, et al.
Publicado: (2021)

Immune Mechanisms of Resistance to Cediranib in Ovarian Cancer
por: Gopinathan, Ganga, et al.
Publicado: (2022)

Circulating biomarkers during treatment in patients with advanced biliary tract cancer receiving cediranib in the UK ABC-03 trial
por: Backen, Alison C., et al.
Publicado: (2018)

Cediranib or placebo in combination with cisplatin and gemcitabine chemotherapy for patients with advanced biliary tract cancer (ABC-03): a randomised phase 2 trial
por: Valle, Juan W, et al.
Publicado: (2015)

Randomized Phase II Trial of Sunitinib or Cediranib in Alveolar Soft Part Sarcoma
por: Nguyen, James, et al.
Publicado: (2023)

Prognostic/predictive value of 207 serum factors in colorectal cancer treated with cediranib and/or chemotherapy
por: Spencer, S K M, et al.
Publicado: (2013)

Synergistic Antivascular and Antitumor Efficacy with Combined Cediranib and SC6889 in Intracranial Mouse Glioma
por: Lobo, Merryl R., et al.
Publicado: (2015)

Randomized Trial of Olaparib With or Without Cediranib for Metastatic Castration-Resistant Prostate Cancer: The Results From National Cancer Institute 9984
por: Kim, Joseph W., et al.
Publicado: (2023)

Combined Efficacy of Cediranib and Quinacrine in Glioma Is Enhanced by Hypoxia and Causally Linked to Autophagic Vacuole Accumulation
por: Lobo, Merryl R., et al.
Publicado: (2014)

Identification of target genes of cediranib in alveolar soft part sarcoma using a gene microarray
por: Jiang, Wenhua, et al.
Publicado: (2017)

Comparison of paclitaxel liposomes combined with carboplatin versus paclitaxel combined with carboplatin in the treatment of advanced ovarian cancer
por: Tan, Xiangbin, et al.
Publicado: (2023)

Travel photography : a complete guide to how to shoot and sell /
por: McCartney, Susan
Publicado: (1992)

Jeremy Hunt’s bizarre ideas show that he doesn’t understand general practice
por: McCartney, Margaret
Publicado: (2014)

Margaret McCartney: What use is mass flu vaccination?
por: McCartney, Margaret
Publicado: (2014)

Margaret McCartney: Passing the patient
por: McCartney, Margaret
Publicado: (2016)

Margaret McCartney: Glasgow’s lost hospital beds
por: McCartney, Margaret
Publicado: (2016)

Margaret McCartney: Stop playing politics with illegal drug use
por: McCartney, Margaret
Publicado: (2014)

Margaret McCartney: The Care Quality Commission is not fit for purpose
por: McCartney, Margaret
Publicado: (2014)

Margaret McCartney: Industry’s interest in diagnosing more dementia
por: McCartney, Margaret
Publicado: (2014)

Margaret McCartney: Do patients know that their records aren’t private?
por: McCartney, Margaret
Publicado: (2014)

Benefits, harms and evidence – reflections from UK primary healthcare
por: McCartney, Margaret
Publicado: (2017)

Pandemics past and dystopian futures
por: McCartney, Margaret
Publicado: (2020)

Medicine: before COVID-19, and after
por: McCartney, Margaret
Publicado: (2020)

Streamlined forensic reporting: Rhetoric and reality
por: McCartney, Carole
Publicado: (2019)

Long-term Remission Over Six Years for a Patient with Recurrent Glioblastoma Treated with Cediranib/Lomustine
por: Drazin, Doniel, et al.
Publicado: (2016)

Quality of life with cediranib in relapsed ovarian cancer: The ICON6 phase 3 randomized clinical trial
por: Stark, Dan P., et al.
Publicado: (2017)

Advantages of Tyrosine Kinase Anti-Angiogenic Cediranib over Bevacizumab: Cell Cycle Abrogation and Synergy with Chemotherapy
por: Bi, Jianling, et al.
Publicado: (2021)

Randomised phase II trial of olaparib, chemotherapy or olaparib and cediranib in patients with platinum-resistant ovarian cancer (OCTOVA): a study protocol
por: Mansouri, Anita, et al.
Publicado: (2021)

Phase I Trial of Ipatasertib Plus Carboplatin, Carboplatin/Paclitaxel, or Capecitabine and Atezolizumab in Metastatic Triple-Negative Breast Cancer
por: Yuan, Yuan, et al.
Publicado: (2023)

EXPERIMENTS ON THE SURVIVAL OF THE FEBRILE HERPETIC AND ALLIED VIRUSES IN VITRO
por: McCartney, James E.
Publicado: (1924)

BRAIN LESIONS OF THE DOMESTIC RABBIT
por: McCartney, James E.
Publicado: (1924)

Sex-Based Vaccine Response in the Context of COVID-19
por: McCartney, Patricia Robin
Publicado: (2020)

Immune Globulin Subcutaneous (Human) 20%: In Primary Immunodeficiency Disorders
por: McCormack, Paul L.
Publicado: (2012)

A phase I study of the combination of ro4929097 and cediranib in patients with advanced solid tumours (PJC-004/NCI 8503)
por: Sahebjam, S, et al.
Publicado: (2013)

Cediranib with mFOLFOX6 vs bevacizumab with mFOLFOX6 in previously treated metastatic colorectal cancer
por: Cunningham, D, et al.
Publicado: (2013)

Clinical Activity and Safety of Cediranib and Olaparib Combination in Patients with Metastatic Pancreatic Ductal Adenocarcinoma without BRCA Mutation
por: Kim, Joseph W., et al.
Publicado: (2021)

Cediranib in patients with alveolar soft-part sarcoma (CASPS): a double-blind, placebo-controlled, randomised, phase 2 trial
por: Judson, Ian, et al.
Publicado: (2019)

Ischemic Colitis Associated with Paclitaxel and Carboplatin Combination
por: Elsayed, Ahmed Gamal, et al.
Publicado: (2017)

Optics of the atmosphere : scattering by molecules and particles /
por: McCartney, Earl J., 1908-
Publicado: (1976)

Cannot write session to /tmp/vufind_sessions/sess_evdiuqkkvvr2ntmr4umrq0lcd5