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Hippocampal Transcriptome Profile of Persistent Memory Rescue in a Mouse Model of THRA1 Mutation-Mediated Resistance to Thyroid Hormone

Hypothyroidism due to THRA1 (gene coding for thyroid hormone receptor α1) mutation-mediated Resistance to Thyroid Hormone (RTH) has been recently reported in human and is associated with memory deficits similar to those found in a mouse model for Thra1 mutation mediated RTH (Thra1(+/m) mice). Here,...

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Detalles Bibliográficos
Autores principales: Wang, Yiqiao, Fisahn, André, Sinha, Indranil, Nguyen, Dinh Phong, Sterzenbach, Ulrich, Lallemend, Francois, Hadjab, Saїda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705459/
https://www.ncbi.nlm.nih.gov/pubmed/26743578
http://dx.doi.org/10.1038/srep18617