Cargando…

The ATM- and ATR-related SCD domain is over-represented in proteins involved in nervous system development

ATM and ATR are cellular kinases with a well-characterized role in the DNA-damage response. Although the complete set of ATM/ATR targets is unknown, they often contain clusters of S/TQ motifs that constitute an SCD domain. In this study, we identified putative ATM/ATR targets that have a conserved S...

Descripción completa

Detalles Bibliográficos
Autores principales: Cara, Lukas, Baitemirova, Medina, Follis, Jack, Larios-Sanz, Maia, Ribes-Zamora, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705472/
https://www.ncbi.nlm.nih.gov/pubmed/26743489
http://dx.doi.org/10.1038/srep19050