Biochemical Characterization of Nonamer Binding Domain of RAG1 Reveals its Thymine Preference with Respect to Length and Position

RAG complex consisting of RAG1 and RAG2 is a site-specific endonuclease responsible for the generation of antigen receptor diversity. It cleaves recombination signal sequence (RSS), comprising of conserved heptamer and nonamer. Nonamer binding domain (NBD) of RAG1 plays a central role in the recogni...

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Detalles Bibliográficos
Autores principales: Raveendran, Deepthi, Raghavan, Sathees C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705477/
https://www.ncbi.nlm.nih.gov/pubmed/26742581
http://dx.doi.org/10.1038/srep19091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705477/
https://www.ncbi.nlm.nih.gov/pubmed/26742581
http://dx.doi.org/10.1038/srep19091

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