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A Generic Platform for Cellular Screening Against Ubiquitin Ligases

Ubiquitin signalling regulates most aspects of cellular life, thus deregulation of ubiquitylation has been linked with a number of diseases. E3 ubiquitin ligases provide substrate selectivity in ubiquitylation cascades and are therefore considered to be attractive targets for developing therapeutic...

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Detalles Bibliográficos
Autores principales:	Maculins, Timurs, Carter, Nikki, Dorval, Thierry, Hudson, Kevin, Nissink, J. Willem M., Hay, Ronald T., Alwan, Husam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705515/ https://www.ncbi.nlm.nih.gov/pubmed/26743172 http://dx.doi.org/10.1038/srep18940

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