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Enhancing immunogenicity and transmission-blocking activity of malaria vaccines by fusing Pfs25 to IMX313 multimerization technology

Transmission-blocking vaccines (TBV) target the sexual-stages of the malaria parasite in the mosquito midgut and are widely considered to be an essential tool for malaria elimination. High-titer functional antibodies are required against target antigens to achieve effective transmission-blocking act...

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Detalles Bibliográficos
Autores principales:	Li, Yuanyuan, Leneghan, Darren B., Miura, Kazutoyo, Nikolaeva, Daria, Brian, Iona J., Dicks, Matthew D. J., Fyfe, Alex J., Zakutansky, Sarah E., de Cassan, Simone, Long, Carole A., Draper, Simon J., Hill, Adrian V. S., Hill, Fergal, Biswas, Sumi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705524/ https://www.ncbi.nlm.nih.gov/pubmed/26743316 http://dx.doi.org/10.1038/srep18848

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