A high-density SNP panel reveals extensive diversity, frequent recombination and multiple recombination hotspots within the chicken major histocompatibility complex B region between BG2 and CD1A1

BACKGROUND: The major histocompatibility complex (MHC) is present within the genomes of all jawed vertebrates. MHC genes are especially important in regulating immune responses, but even after over 80 years of research on the MHC, much remains to be learned about how it influences adaptive and innat...

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Detalles Bibliográficos
Autores principales: Fulton, Janet E., McCarron, Amy M., Lund, Ashlee R., Pinegar, Kara N., Wolc, Anna, Chazara, Olympe, Bed’Hom, Bertrand, Berres, Mark, Miller, Marcia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705597/
https://www.ncbi.nlm.nih.gov/pubmed/26743767
http://dx.doi.org/10.1186/s12711-015-0181-x

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