Secondary structure encodes a cooperative tertiary folding funnel in the Azoarcus ribozyme

A requirement for specific RNA folding is that the free-energy landscape discriminate against non-native folds. While tertiary interactions are critical for stabilizing the native fold, they are relatively non-specific, suggesting additional mechanisms contribute to tertiary folding specificity. In...

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Detalles Bibliográficos
Autores principales: Mustoe, Anthony M., Al-Hashimi, Hashim M., Brooks, Charles L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705646/
https://www.ncbi.nlm.nih.gov/pubmed/26481360
http://dx.doi.org/10.1093/nar/gkv1055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705646/
https://www.ncbi.nlm.nih.gov/pubmed/26481360
http://dx.doi.org/10.1093/nar/gkv1055

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