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Secondary structure encodes a cooperative tertiary folding funnel in the Azoarcus ribozyme
A requirement for specific RNA folding is that the free-energy landscape discriminate against non-native folds. While tertiary interactions are critical for stabilizing the native fold, they are relatively non-specific, suggesting additional mechanisms contribute to tertiary folding specificity. In...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705646/ https://www.ncbi.nlm.nih.gov/pubmed/26481360 http://dx.doi.org/10.1093/nar/gkv1055 |