Human telomerase reverse transcriptase binds to a pre-organized hTR in vivo exposing its template

Telomerase is a specialized reverse transcriptase that is responsible for telomere length maintenance. As in other organisms, the minimal components required for an active human telomerase are the template-providing telomerase RNA (hTR) and the enzymatic entity telomerase reverse transcriptase (hTER...

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Detalles Bibliográficos
Autores principales: Zemora, Georgeta, Handl, Stefan, Waldsich, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705647/
https://www.ncbi.nlm.nih.gov/pubmed/26481359
http://dx.doi.org/10.1093/nar/gkv1065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705647/
https://www.ncbi.nlm.nih.gov/pubmed/26481359
http://dx.doi.org/10.1093/nar/gkv1065

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