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Human telomerase reverse transcriptase binds to a pre-organized hTR in vivo exposing its template

Telomerase is a specialized reverse transcriptase that is responsible for telomere length maintenance. As in other organisms, the minimal components required for an active human telomerase are the template-providing telomerase RNA (hTR) and the enzymatic entity telomerase reverse transcriptase (hTER...

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Detalles Bibliográficos
Autores principales:	Zemora, Georgeta, Handl, Stefan, Waldsich, Christina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705647/ https://www.ncbi.nlm.nih.gov/pubmed/26481359 http://dx.doi.org/10.1093/nar/gkv1065

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