Cargando…

Death of a dogma: eukaryotic mRNAs can code for more than one protein

mRNAs carry the genetic information that is translated by ribosomes. The traditional view of a mature eukaryotic mRNA is a molecule with three main regions, the 5′ UTR, the protein coding open reading frame (ORF) or coding sequence (CDS), and the 3′ UTR. This concept assumes that ribosomes translate...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mouilleron, Hélène, Delcourt, Vivian, Roucou, Xavier
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Survey and Summary
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705651/ https://www.ncbi.nlm.nih.gov/pubmed/26578573 http://dx.doi.org/10.1093/nar/gkv1218

Ejemplares similares

Experimental approaches to identify non-coding RNAs
por: Hüttenhofer, Alexander, et al.
Publicado: (2006)

DNA G-quadruplex structures: more than simple roadblocks to transcription?
por: Robinson, Jenna, et al.
Publicado: (2021)

Ribosomal frameshifting in decoding antizyme mRNAs from yeast and protists to humans: close to 300 cases reveal remarkable diversity despite underlying conservation
por: Ivanov, Ivaylo P., et al.
Publicado: (2007)

Emerging functional and mechanistic paradigms of mammalian long non-coding RNAs
por: Moran, Victoria A., et al.
Publicado: (2012)

More than a decade of developmental gene expression atlases: where are we now?
por: de Boer, Bouke A., et al.
Publicado: (2009)

The current state of eukaryotic DNA base damage and repair
por: Bauer, Nicholas C., et al.
Publicado: (2015)

Insights into the mechanisms of eukaryotic translation gained with ribosome profiling
por: Andreev, Dmitry E., et al.
Publicado: (2017)

Molecular mechanisms of eukaryotic pre-mRNA 3′ end processing regulation
por: Millevoi, Stefania, et al.
Publicado: (2010)

Analysis of the eukaryotic topoisomerase II DNA gate: a single-molecule FRET and structural perspective
por: Collins, Tammy R. L., et al.
Publicado: (2009)

The interaction networks of structured RNAs
por: Lescoute, A., et al.
Publicado: (2006)

Splicing regulation by long noncoding RNAs
por: Romero-Barrios, Natali, et al.
Publicado: (2018)

Functional diversity of small nucleolar RNAs
por: Bratkovič, Tomaž, et al.
Publicado: (2020)

Protein–DNA binding: complexities and multi-protein codes
por: Siggers, Trevor, et al.
Publicado: (2014)

An integrated, structure- and energy-based view of the genetic code
por: Grosjean, Henri, et al.
Publicado: (2016)

Type II restriction endonucleases—a historical perspective and more
por: Pingoud, Alfred, et al.
Publicado: (2014)

Sequence-specific binding of single-stranded RNA: is there a code for recognition?
por: Auweter, Sigrid D., et al.
Publicado: (2006)

Multiple roles of the coding sequence 5′ end in gene expression regulation
por: Tuller, Tamir, et al.
Publicado: (2015)

MBNL proteins and their target RNAs, interaction and splicing regulation
por: Konieczny, Patryk, et al.
Publicado: (2014)

Microarrays for identifying binding sites and probing structure of RNAs
por: Kierzek, Ryszard, et al.
Publicado: (2015)

Conserved non-coding elements: developmental gene regulation meets genome organization
por: Polychronopoulos, Dimitris, et al.
Publicado: (2017)

Cellular versus viral microRNAs in host–virus interaction
por: Ghosh, Zhumur, et al.
Publicado: (2009)

Chemistry, mechanism and clinical status of antisense oligonucleotides and duplex RNAs
por: Shen, Xiulong, et al.
Publicado: (2018)

Identifying proteins that bind to specific RNAs - focus on simple repeat expansion diseases
por: Jazurek, Magdalena, et al.
Publicado: (2016)

Systems biology-based investigation of cooperating microRNAs as monotherapy or adjuvant therapy in cancer
por: Lai, Xin, et al.
Publicado: (2019)

Transcriptional interference at tandem lncRNA and protein-coding genes: an emerging theme in regulation of cellular nutrient homeostasis
por: Shuman, Stewart
Publicado: (2020)

Lessons from miR-143/145: the importance of cell-type localization of miRNAs
por: Kent, Oliver A., et al.
Publicado: (2014)

A base pair at the bottom of the anticodon stem is reciprocally preferred for discrimination of cognate tRNAs by Escherichia coli lysyl- and glutaminyl-tRNA synthetases
por: Fukunaga, Jun-ichi, et al.
Publicado: (2006)

Unraveling helicase mechanisms one molecule at a time
por: Rasnik, Ivan, et al.
Publicado: (2006)

Combined cytotoxic chemotherapy and immunotherapy of cancer: modern times
por: Bailly, Christian, et al.
Publicado: (2020)

DNA mechanics as a tool to probe helicase and translocase activity
por: Lionnet, Timothée, et al.
Publicado: (2006)

γ-H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatin
por: Kinner, Andrea, et al.
Publicado: (2008)

Survey of group I and group II introns in 29 sequenced genomes of the Bacillus cereus group: insights into their spread and evolution
por: Tourasse, Nicolas J., et al.
Publicado: (2008)

Structural and evolutionary classification of Type II restriction enzymes based on theoretical and experimental analyses
por: Orlowski, Jerzy, et al.
Publicado: (2008)

Mechanisms and strategies for effective delivery of antisense and siRNA oligonucleotides
por: Juliano, Rudy, et al.
Publicado: (2008)

See me, feel me: methods to concurrently visualize and manipulate single DNA molecules and associated proteins
por: van Mameren, Joost, et al.
Publicado: (2008)

Specificity of DNA microarray hybridization: characterization, effectors and approaches for data correction
por: Koltai, Hinanit, et al.
Publicado: (2008)

Presence and role of cytosine methylation in DNA viruses of animals
por: Hoelzer, Karin, et al.
Publicado: (2008)

The triple helix: 50 years later, the outcome
por: Duca, Maria, et al.
Publicado: (2008)

MECP2 genomic structure and function: insights from ENCODE
por: Singh, Jasmine, et al.
Publicado: (2008)

Genomics of bacteria and archaea: the emerging dynamic view of the prokaryotic world
por: Koonin, Eugene V., et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_e21a0lrhhbnnqlmod83ivsfvcr