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Exploded view of higher order G-quadruplex structures through click-chemistry assisted single-molecule mechanical unfolding
Due to the long-range nature of high-order interactions between distal components in a biomolecule, transition dynamics of tertiary structures is often too complex to profile using conventional methods. Inspired by the exploded view in mechanical drawing, here, we used laser tweezers to mechanically...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705664/ https://www.ncbi.nlm.nih.gov/pubmed/26626151 http://dx.doi.org/10.1093/nar/gkv1326 |