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Systematic identification and annotation of human methylation marks based on bisulfite sequencing methylomes reveals distinct roles of cell type-specific hypomethylation in the regulation of cell identity genes
DNA methylation is a key epigenetic mark that is critical for gene regulation in multicellular eukaryotes. Although various human cell types may have the same genome, these cells have different methylomes. The systematic identification and characterization of methylation marks across cell types are...
Autores principales: | Liu, Hongbo, Liu, Xiaojuan, Zhang, Shumei, Lv, Jie, Li, Song, Shang, Shipeng, Jia, Shanshan, Wei, Yanjun, Wang, Fang, Su, Jianzhong, Wu, Qiong, Zhang, Yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705665/ https://www.ncbi.nlm.nih.gov/pubmed/26635396 http://dx.doi.org/10.1093/nar/gkv1332 |
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