Induction of cap-independent BiP (hsp-3) and Bcl-2 (ced-9) translation in response to eIF4G (IFG-1) depletion in C. elegans

During apoptosis, activated caspases cleave the translation initiation factor eIF4G. This cleavage disrupts cap-dependent mRNA translation initiation within the cell. However, a specific subset of mRNAs can still be recruited for protein synthesis in a cap-independent manner by the residual initiati...

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Detalles Bibliográficos
Autores principales: Morrison, J Kaitlin, Friday, Andrew J, Henderson, Melissa A, Hao, Enhui, Keiper, Brett D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705828/
https://www.ncbi.nlm.nih.gov/pubmed/26779406
http://dx.doi.org/10.4161/trla.28935

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705828/
https://www.ncbi.nlm.nih.gov/pubmed/26779406
http://dx.doi.org/10.4161/trla.28935

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