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Mechanistic and Kinetic Differences between Reverse Transcriptases of Vpx Coding and Non-coding Lentiviruses

Among lentiviruses, HIV Type 2 (HIV-2) and many simian immunodeficiency virus (SIV) strains replicate rapidly in non-dividing macrophages, whereas HIV Type 1 (HIV-1) replication in this cell type is kinetically delayed. The efficient replication capability of HIV-2/SIV in non-dividing cells is induc...

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Detalles Bibliográficos
Autores principales:	Lenzi, Gina M., Domaoal, Robert A., Kim, Dong-Hyun, Schinazi, Raymond F., Kim, Baek
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2015
Materias:	DNA and Chromosomes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705996/ https://www.ncbi.nlm.nih.gov/pubmed/26483545 http://dx.doi.org/10.1074/jbc.M115.691576

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