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Lack of association between TDP-43 pathology and tau mis-splicing in Alzheimer's disease

A proportion of Alzheimer's disease cases displays inclusions of the RNA-binding protein, TDP-43. Considering the pathogenic role of tau mis-splicing, we compared tau isoform expression between Alzheimer's disease cases with or without TDP-43 inclusions. The average ratio of tau isoforms c...

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Detalles Bibliográficos
Autores principales:	Niblock, Michael, Hortobágyi, Tibor, Troakes, Claire, Al-Sarraj, Safa, Spickett, Carl, Jones, Rebecca, Shaw, Christopher E., Gallo, Jean-Marc
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706155/ https://www.ncbi.nlm.nih.gov/pubmed/26507309 http://dx.doi.org/10.1016/j.neurobiolaging.2015.09.022

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