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Genetically Determined MBL Deficiency Is Associated with Protection against Chronic Cardiomyopathy in Chagas Disease

Chagas disease (CD) is caused by Trypanosoma cruzi, whose sugar moieties are recognized by mannan binding lectin (MBL), a soluble pattern-recognition molecule that activates the lectin pathway of complement. MBL levels and protein activity are affected by polymorphisms in the MBL2 gene. We sequenced...

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Detalles Bibliográficos
Autores principales:	Luz, Paola Rosa, Miyazaki, Márcia I., Chiminacio Neto, Nelson, Padeski, Marcela C., Barros, Ana Cláudia M., Boldt, Angelica B. W., Messias-Reason, Iara J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706301/ https://www.ncbi.nlm.nih.gov/pubmed/26745156 http://dx.doi.org/10.1371/journal.pntd.0004257

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