Insulin detemir may be less efficacious in patients with nonalcoholic fatty liver disease and hypertriglyceridemia

Insulin detemir is commonly used in obese patients with diabetes mellitus as it is considered hepatoselective and causes less weight gain. We describe a relative lack of effectiveness of detemir in patients with significant NAFLD and hypertriglyceridemia, compared to isophane insulin. This may affec...

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Detalles Bibliográficos
Autores principales: Whyte, Martin, Quaglia, Alberto, Hopkins, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706392/
https://www.ncbi.nlm.nih.gov/pubmed/26783443
http://dx.doi.org/10.1002/ccr3.458
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author Whyte, Martin
Quaglia, Alberto
Hopkins, David
author_facet Whyte, Martin
Quaglia, Alberto
Hopkins, David
author_sort Whyte, Martin
collection PubMed
description Insulin detemir is commonly used in obese patients with diabetes mellitus as it is considered hepatoselective and causes less weight gain. We describe a relative lack of effectiveness of detemir in patients with significant NAFLD and hypertriglyceridemia, compared to isophane insulin. This may affect how such patients are managed with insulin.
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spelling pubmed-47063922016-01-18 Insulin detemir may be less efficacious in patients with nonalcoholic fatty liver disease and hypertriglyceridemia Whyte, Martin Quaglia, Alberto Hopkins, David Clin Case Rep Case Reports Insulin detemir is commonly used in obese patients with diabetes mellitus as it is considered hepatoselective and causes less weight gain. We describe a relative lack of effectiveness of detemir in patients with significant NAFLD and hypertriglyceridemia, compared to isophane insulin. This may affect how such patients are managed with insulin. John Wiley and Sons Inc. 2015-12-01 /pmc/articles/PMC4706392/ /pubmed/26783443 http://dx.doi.org/10.1002/ccr3.458 Text en © 2015 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs (http://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Reports
Whyte, Martin
Quaglia, Alberto
Hopkins, David
Insulin detemir may be less efficacious in patients with nonalcoholic fatty liver disease and hypertriglyceridemia
title Insulin detemir may be less efficacious in patients with nonalcoholic fatty liver disease and hypertriglyceridemia
title_full Insulin detemir may be less efficacious in patients with nonalcoholic fatty liver disease and hypertriglyceridemia
title_fullStr Insulin detemir may be less efficacious in patients with nonalcoholic fatty liver disease and hypertriglyceridemia
title_full_unstemmed Insulin detemir may be less efficacious in patients with nonalcoholic fatty liver disease and hypertriglyceridemia
title_short Insulin detemir may be less efficacious in patients with nonalcoholic fatty liver disease and hypertriglyceridemia
title_sort insulin detemir may be less efficacious in patients with nonalcoholic fatty liver disease and hypertriglyceridemia
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706392/
https://www.ncbi.nlm.nih.gov/pubmed/26783443
http://dx.doi.org/10.1002/ccr3.458
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