Isodicentric Philadelphia chromosome: an uncommon chromosomal abnormality in the chronic phase of chronic myeloid leukemia (CML)

An isodicentric Philadelphia chromosome is an uncommon finding previously described as a secondary chromosomal abnormality in accelerated‐ or blast‐phase of chronic myeloid leukemia (CML) with resistance to imatinib mesylate or dasatinib. Here, we present a case with idic(Ph) chromosome identified a...

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Detalles Bibliográficos
Autores principales: Loo, Eric, Bansal, Pranshu, Cherukuri, Durga, Arana Yi, Cecilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706395/
https://www.ncbi.nlm.nih.gov/pubmed/26783434
http://dx.doi.org/10.1002/ccr3.444
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author Loo, Eric
Bansal, Pranshu
Cherukuri, Durga
Arana Yi, Cecilia
author_facet Loo, Eric
Bansal, Pranshu
Cherukuri, Durga
Arana Yi, Cecilia
author_sort Loo, Eric
collection PubMed
description An isodicentric Philadelphia chromosome is an uncommon finding previously described as a secondary chromosomal abnormality in accelerated‐ or blast‐phase of chronic myeloid leukemia (CML) with resistance to imatinib mesylate or dasatinib. Here, we present a case with idic(Ph) chromosome identified at initial diagnosis in a patient with chronic‐phase CML.
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spelling pubmed-47063952016-01-18 Isodicentric Philadelphia chromosome: an uncommon chromosomal abnormality in the chronic phase of chronic myeloid leukemia (CML) Loo, Eric Bansal, Pranshu Cherukuri, Durga Arana Yi, Cecilia Clin Case Rep Case Reports An isodicentric Philadelphia chromosome is an uncommon finding previously described as a secondary chromosomal abnormality in accelerated‐ or blast‐phase of chronic myeloid leukemia (CML) with resistance to imatinib mesylate or dasatinib. Here, we present a case with idic(Ph) chromosome identified at initial diagnosis in a patient with chronic‐phase CML. John Wiley and Sons Inc. 2015-11-19 /pmc/articles/PMC4706395/ /pubmed/26783434 http://dx.doi.org/10.1002/ccr3.444 Text en © 2015 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial (http://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Case Reports
Loo, Eric
Bansal, Pranshu
Cherukuri, Durga
Arana Yi, Cecilia
Isodicentric Philadelphia chromosome: an uncommon chromosomal abnormality in the chronic phase of chronic myeloid leukemia (CML)
title Isodicentric Philadelphia chromosome: an uncommon chromosomal abnormality in the chronic phase of chronic myeloid leukemia (CML)
title_full Isodicentric Philadelphia chromosome: an uncommon chromosomal abnormality in the chronic phase of chronic myeloid leukemia (CML)
title_fullStr Isodicentric Philadelphia chromosome: an uncommon chromosomal abnormality in the chronic phase of chronic myeloid leukemia (CML)
title_full_unstemmed Isodicentric Philadelphia chromosome: an uncommon chromosomal abnormality in the chronic phase of chronic myeloid leukemia (CML)
title_short Isodicentric Philadelphia chromosome: an uncommon chromosomal abnormality in the chronic phase of chronic myeloid leukemia (CML)
title_sort isodicentric philadelphia chromosome: an uncommon chromosomal abnormality in the chronic phase of chronic myeloid leukemia (cml)
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706395/
https://www.ncbi.nlm.nih.gov/pubmed/26783434
http://dx.doi.org/10.1002/ccr3.444
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