Vacuolated lymphocytes signifying a metabolic disorder in an infant with developmental delay

Metabolic disorders sometimes cause accumulation of metabolic byproducts which are manifested as cytoplasmic vacuoles in lymphocytes. We report the case of an infant with final diagnosis of GM1 gangliosidosis who initially presented with developmental delay and peripheral blood vacuolated lymphocyte...

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Detalles Bibliográficos
Autores principales: Salama, Rasha, Zhou, Jiehao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Clinical Images
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706402/
https://www.ncbi.nlm.nih.gov/pubmed/26783448
http://dx.doi.org/10.1002/ccr3.447
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author Salama, Rasha
Zhou, Jiehao
author_facet Salama, Rasha
Zhou, Jiehao
author_sort Salama, Rasha
collection PubMed
description Metabolic disorders sometimes cause accumulation of metabolic byproducts which are manifested as cytoplasmic vacuoles in lymphocytes. We report the case of an infant with final diagnosis of GM1 gangliosidosis who initially presented with developmental delay and peripheral blood vacuolated lymphocytes. Blood film review is recommended in children suspicious for metabolic disorders.
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spelling pubmed-47064022016-01-18 Vacuolated lymphocytes signifying a metabolic disorder in an infant with developmental delay Salama, Rasha Zhou, Jiehao Clin Case Rep Clinical Images Metabolic disorders sometimes cause accumulation of metabolic byproducts which are manifested as cytoplasmic vacuoles in lymphocytes. We report the case of an infant with final diagnosis of GM1 gangliosidosis who initially presented with developmental delay and peripheral blood vacuolated lymphocytes. Blood film review is recommended in children suspicious for metabolic disorders. John Wiley and Sons Inc. 2015-11-19 /pmc/articles/PMC4706402/ /pubmed/26783448 http://dx.doi.org/10.1002/ccr3.447 Text en © 2015 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs (http://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Clinical Images
Salama, Rasha
Zhou, Jiehao
Vacuolated lymphocytes signifying a metabolic disorder in an infant with developmental delay
title Vacuolated lymphocytes signifying a metabolic disorder in an infant with developmental delay
title_full Vacuolated lymphocytes signifying a metabolic disorder in an infant with developmental delay
title_fullStr Vacuolated lymphocytes signifying a metabolic disorder in an infant with developmental delay
title_full_unstemmed Vacuolated lymphocytes signifying a metabolic disorder in an infant with developmental delay
title_short Vacuolated lymphocytes signifying a metabolic disorder in an infant with developmental delay
title_sort vacuolated lymphocytes signifying a metabolic disorder in an infant with developmental delay
topic Clinical Images
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706402/
https://www.ncbi.nlm.nih.gov/pubmed/26783448
http://dx.doi.org/10.1002/ccr3.447
work_keys_str_mv AT salamarasha vacuolatedlymphocytessignifyingametabolicdisorderinaninfantwithdevelopmentaldelay
AT zhoujiehao vacuolatedlymphocytessignifyingametabolicdisorderinaninfantwithdevelopmentaldelay

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