In Vitro Mode of Action and Anti-thrombotic Activity of Boophilin, a Multifunctional Kunitz Protease Inhibitor from the Midgut of a Tick Vector of Babesiosis, Rhipicephalus microplus

BACKGROUND: Hematophagous mosquitos and ticks avoid host hemostatic system through expression of enzyme inhibitors targeting proteolytic reactions of the coagulation and complement cascades. While most inhibitors characterized to date were found in the salivary glands, relatively few others have bee...

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Detalles Bibliográficos
Autores principales: Assumpção, Teresa C., Ma, Dongying, Mizurini, Daniella M., Kini, R. Manjunatha, Ribeiro, José M. C., Kotsyfakis, Michail, Monteiro, Robson Q., Francischetti, Ivo M. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706430/
https://www.ncbi.nlm.nih.gov/pubmed/26745503
http://dx.doi.org/10.1371/journal.pntd.0004298

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706430/
https://www.ncbi.nlm.nih.gov/pubmed/26745503
http://dx.doi.org/10.1371/journal.pntd.0004298

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