Prognostic value of body mass index before treatment for laryngeal squamous cell carcinoma

OBJECTIVE: Patients with head and neck cancer often suffer from malnutrition. This study aims to investigate the influence of body mass index (BMI) on the prognosis of laryngeal squamous cell carcinoma (LSCC). METHODS: A total of 473 patients with LSCC initially treated at Sun Yat-sen University Can...

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Detalles Bibliográficos
Autores principales: Li, Zhao-Qu, Zou, Lan, Liu, Tian-Run, Yang, An-Kui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Anti-Cancer Association 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706531/
https://www.ncbi.nlm.nih.gov/pubmed/26779376
http://dx.doi.org/10.7497/j.issn.2095-3941.2015.0043
Descripción
Sumario:OBJECTIVE: Patients with head and neck cancer often suffer from malnutrition. This study aims to investigate the influence of body mass index (BMI) on the prognosis of laryngeal squamous cell carcinoma (LSCC). METHODS: A total of 473 patients with LSCC initially treated at Sun Yat-sen University Cancer Center between January 2005 and July 2009 were retrospectively reviewed. Survival analysis was performed by the Kaplan-Meier method and Cox regression model. RESULTS: Low BMI before treatment was significantly associated with poor overall survival in patients with LSCC (P<0.001). BMI was an independent prognostic factor for patients with LSCC. CONCLUSION: Leanness before treatment was associated with poor prognosis in patients with LSCC. Good nutritional status is favorable to improve survival in patients with LSCC.

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