Prognostic value of body mass index before treatment for laryngeal squamous cell carcinoma

OBJECTIVE: Patients with head and neck cancer often suffer from malnutrition. This study aims to investigate the influence of body mass index (BMI) on the prognosis of laryngeal squamous cell carcinoma (LSCC). METHODS: A total of 473 patients with LSCC initially treated at Sun Yat-sen University Can...

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Detalles Bibliográficos
Autores principales: Li, Zhao-Qu, Zou, Lan, Liu, Tian-Run, Yang, An-Kui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Anti-Cancer Association 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706531/
https://www.ncbi.nlm.nih.gov/pubmed/26779376
http://dx.doi.org/10.7497/j.issn.2095-3941.2015.0043
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author Li, Zhao-Qu
Zou, Lan
Liu, Tian-Run
Yang, An-Kui
author_facet Li, Zhao-Qu
Zou, Lan
Liu, Tian-Run
Yang, An-Kui
author_sort Li, Zhao-Qu
collection PubMed
description OBJECTIVE: Patients with head and neck cancer often suffer from malnutrition. This study aims to investigate the influence of body mass index (BMI) on the prognosis of laryngeal squamous cell carcinoma (LSCC). METHODS: A total of 473 patients with LSCC initially treated at Sun Yat-sen University Cancer Center between January 2005 and July 2009 were retrospectively reviewed. Survival analysis was performed by the Kaplan-Meier method and Cox regression model. RESULTS: Low BMI before treatment was significantly associated with poor overall survival in patients with LSCC (P<0.001). BMI was an independent prognostic factor for patients with LSCC. CONCLUSION: Leanness before treatment was associated with poor prognosis in patients with LSCC. Good nutritional status is favorable to improve survival in patients with LSCC.
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spelling pubmed-47065312016-01-15 Prognostic value of body mass index before treatment for laryngeal squamous cell carcinoma Li, Zhao-Qu Zou, Lan Liu, Tian-Run Yang, An-Kui Cancer Biol Med Original Article OBJECTIVE: Patients with head and neck cancer often suffer from malnutrition. This study aims to investigate the influence of body mass index (BMI) on the prognosis of laryngeal squamous cell carcinoma (LSCC). METHODS: A total of 473 patients with LSCC initially treated at Sun Yat-sen University Cancer Center between January 2005 and July 2009 were retrospectively reviewed. Survival analysis was performed by the Kaplan-Meier method and Cox regression model. RESULTS: Low BMI before treatment was significantly associated with poor overall survival in patients with LSCC (P<0.001). BMI was an independent prognostic factor for patients with LSCC. CONCLUSION: Leanness before treatment was associated with poor prognosis in patients with LSCC. Good nutritional status is favorable to improve survival in patients with LSCC. Chinese Anti-Cancer Association 2015-12 /pmc/articles/PMC4706531/ /pubmed/26779376 http://dx.doi.org/10.7497/j.issn.2095-3941.2015.0043 Text en 2015 Cancer Biology & Medicine This work is licensed under a Creative Commons Attribution 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by/3.0/
spellingShingle Original Article
Li, Zhao-Qu
Zou, Lan
Liu, Tian-Run
Yang, An-Kui
Prognostic value of body mass index before treatment for laryngeal squamous cell carcinoma
title Prognostic value of body mass index before treatment for laryngeal squamous cell carcinoma
title_full Prognostic value of body mass index before treatment for laryngeal squamous cell carcinoma
title_fullStr Prognostic value of body mass index before treatment for laryngeal squamous cell carcinoma
title_full_unstemmed Prognostic value of body mass index before treatment for laryngeal squamous cell carcinoma
title_short Prognostic value of body mass index before treatment for laryngeal squamous cell carcinoma
title_sort prognostic value of body mass index before treatment for laryngeal squamous cell carcinoma
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706531/
https://www.ncbi.nlm.nih.gov/pubmed/26779376
http://dx.doi.org/10.7497/j.issn.2095-3941.2015.0043
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AT liutianrun prognosticvalueofbodymassindexbeforetreatmentforlaryngealsquamouscellcarcinoma
AT yangankui prognosticvalueofbodymassindexbeforetreatmentforlaryngealsquamouscellcarcinoma

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