Aggressive cutaneous zygomycosis caused by Apophysomyces variabilis in an immunocompetent child

A zygomycetous fungus was observed in a biopsy of a 9-year-old male. The patient was presented with severe cutaneous lesions subsequent to a traumatic car accident. Following fungal detection, antifungal treatment was prescribed but condition deteriorated rapidly and above knee amputation was done a...

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Detalles Bibliográficos
Autores principales: Al-Zaydani, Ibrahim A., Al-Hakami, Ahmed M., Joseph, Martin R.P., Kassem, Walid M., Almaghrabi, Mohamed K., Nageeb, Abdalla, Hamid, Mohamed E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706566/
https://www.ncbi.nlm.nih.gov/pubmed/26858932
http://dx.doi.org/10.1016/j.mmcr.2015.12.003
Descripción
Sumario:A zygomycetous fungus was observed in a biopsy of a 9-year-old male. The patient was presented with severe cutaneous lesions subsequent to a traumatic car accident. Following fungal detection, antifungal treatment was prescribed but condition deteriorated rapidly and above knee amputation was done as lifesaving and to control fungal infection. Analysis of the 28 S rRNA gene (accession KT149770) aligned the isolate with members of the genus Apophysomyces and the pathogen was identified as Apophysomces variabilis.

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