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Both HDAC5 and HDAC6 are required for the proliferation and metastasis of melanoma cells
BACKGROUND: Histone deacetylase (HDAC) inhibitors are widely used in clinical investigation as novel drug targets. For example, panobinostat and vorinostat have been used to treat patients with melanoma. However, HDAC inhibitors are small-molecule compounds without a specific target, and their mecha...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706654/ https://www.ncbi.nlm.nih.gov/pubmed/26747087 http://dx.doi.org/10.1186/s12967-015-0753-0 |